Article Id 80

Volume 1, Number 3, Year 1999




Sleep,Dream,Hypnosis and Healing:
Behavioral State-Related Gene Expression
and Psychotherapy



Ernest Lawrence Rossi, Ph.D.




Profound advances in research on the molecular-genetic basis of sleep and
dreams have important implications for understanding the deep psychobiological
dynamics of hypnosis,psychotherapy and healing.The essence of this new view
is that Immediate-Early Genes (also called “Primary Response Genes ”or third
messengers)play a central role in the dynamics of waking,sleeping,dreaming,
and mind-body healing at the cellular level.This paper reviews evidence that
immediate-early genes (IEGs)function as mediators of information transduction
between psychological experience,behavioral states,and gene expression.A
wide range of behavioral state-related gene expression (from relaxation,hypnosis
and sleep to high arousal,performance,tress and trauma)culminate in the
production of new proteins for homeostasis,physical and psychosocial adaptation.
Some theoretical and clinical implications of this new view of the deep
psychobiology of consciousness,sleep,dreams,hypnosis and psychotherapy are
explored.(Sleep and Hypnosis 1999;1:141-157)



Keywords: consciousness, sleep, REM, hypnosis, immediate-early genes, psychobiology,
psychotherapy, psychosomatic, behavioral state-related gene expression
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