Article Id 211 Issue 31




Sleep, Energy and Self Rated Cognition Across 7 Nights Following Recreational Ecstasy/MDMA use


K. A. Jones, F. Callen, M.T. Blagrove, Ph.D., A.C Parrott, Ph.D.




Objective: This study aimed to prospectively assess self-rated sleep length and sleep
quality in recreational MDMA users (n= 18, 13 male, 5 female, 19.5 yrs) for the 7 days
following ecstasy consumption, and to compare them to alcohol drinking controls (n=
18, 7 male, 11 female, 20.2yrs).

Method: Time of going to sleep, wake time, total sleep length, sleep quality, and self
rated sleepiness, energy and cognition were assessed. Alcohol use each day was also
reported. Ecstasy was consumed on night 1 for ecstasy users.

Results: Ecstasy users reported significantly reduced sleep time on post-ecstasy nights
2, 3, 4 and 5. They experienced significantly reduced sleep quality on nights 1, 2, 3, 4
and 5. The severest sleep length and sleep quality decrements occurred on nights 2
and 3. Self-rated cognitive measures were significantly impaired on days 3, 4, 5 and 6.
By day 7 all assessment measures were similar to the control group. When controlling
for alcohol use on each day the sleep length and sleep quality differences between the
groups remained significant and the interactions of night or day with group remained
significant.

Conclusions: Impairments in sleep, energy and self-rated cognitive measures occur for
several nights and days following ecstasy use, but are not due to alcohol use across
those days.



Keywords: Ecstasy, MDMA (3, 4- Methylenedioxymethamphetamine), Sleep, Energy, Cognitive measures, Prospective
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