One of the current challenges of sleep
research is to identify how cognitive
processes are altered during sleep. In this
issue, Kolff and her colleagues report
studies that refine our understanding of
how to measure such processes (1), and
extend our knowledge of them (2). Such
studies are not easy to perform. The
standard methodology for studying
cognition, namely the administration of
cognitive tests, cannot be used during sleep,
because of the requirement for overt
responses from subjects. Instead, a series of
circumstantial methodologies must be used.