Article Id 105

Volume 4, Number 1, Year 2002




The Psychosocial Genomics of Therapeutic Hypnosis and Psychotherapy


Ernest Lawrence Rossi Ph.D




Psychosocial genomics is the newly emerging study of how our psychological and
social environment interacts with gene expression in everyday life as well as the cre-
ative dynamics of human experience in the cultural arts,sciences,and healing.The
theory,research,and clinical applications of psychosocial genomics to therapeutic hyp-
nosis,psychotherapy,and the holistic healing arts are outlined.The key concept of psy-
chosocial genomics is that many forms of psychobiological arousal during waking,
sleeping,and dreaming can evoke immediate-early genes (IEGs),behavioral state-relat-
ed gene expression (BSGE),and activity-dependent gene expression (ADGE)to opti-
mize the synthesis of proteins to facilitate neurogenesis,problem solving,and healing
in the 4-stage creative cycle.A summary of the 4-stage creative cycle replaying natu-
ral Darwinian variation and conscious selection for problem solving and symptom res-
olution is illustrated with a videotape of a demonstration of therapeutic hypnosis.
(Sleep and Hypnosis 2002;4(1):26-38)



Keywords: psychosocial genomics, therapeutic hypnosis, psychotherapy, immediate early genes, behavior state-related genes, activity-dependent genes, replay, creative cycle
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