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Exploring Gene Expression in Sleep, Dreams and Hypnosis with the New DNA Microarray Technology: A Call for Clinical-Experimental Research
Ernest Lawrence Rossi
Sleep and Hypnosis: A Journal of Clinical Neuroscience and Psychopathology 2000;2(1):40-46

Sleep, dream, hypnosis and awake states are generally recognized as a continuum of dynamical processes of the organism but current research has not resolved fundamental issues of how this continuum is to be explored. Recently the concept of Behavior State- Related Gene Expression has been introduced to describe how psychobiological states of awake, sleep, dreaming, arousal, novelty, environmental enrichment, physical exercise and stress are associated with different patterns of gene expression. New research techniques are emerging from The Human Genome Research Project that can be used to identify patterns of gene expression in such behavioral states of the organism on the cellular-genetic level. Current research developments in DNA Microarray Technology that are being used to rapidly assess gene expression in the various states of health and disease are discussed as a new approach to characterize the psychobiology of the cell cycle, arousal, stress, sleep, dream and the possible therapeutic applications of hypnosis.
Keywords:
sleep, dreams, therapeutic hypnosis, consciousness, memory, learning, novelty,
psychobiology, behavior state-related gene expression, gene chip microarrays, DNA array
technology

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